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Crizalk 250 Crizotinib Capsule Pfizer




Medicine Detail


Brand Name : Crizalk
Active Ingredients : Crizotinib
Manufactured by: Pfizer, Inc.
Strength: 250 mg
Form: Capsules
Packing: Pack of 60 Capsules

WHAT IS CRIZALK ?

Crizalk is targeted therapy. It is an oral receptor tyrosine kinase inhibitor Crizotinib is a cancer medication that interferes with the growth and spread of cancer cells in the body.

Crizalk is focused on treatment. It is an oral receptor tyrosine kinase inhibitor Crizotinib is a cancer prescription that meddles with the development and spread of cancer cells in the body.

Crizotinib 250 mg Capsules is utilized for the treatment of non-small cell lung cancer that is caused by a deformity in a quality called ALK (anaplastic lymphoma kinase). The cancer must be (ALK)- positive as demonstrated by a FDA-endorsed test. This prescription blocks a catalyst called anaplastic lymphoma kinase (ALK). Some lung cancer cells have an overactive variant of ALK. Blocking ALK with crizotinib can stop the cells developing however it just works in tumors with the overactive compound. Around 1 of every 20 individuals (5%) with non small cell lung cancer (NSCLC) have the overactive ALK catalyst.

MEDICINE USES:


Crizotinib 250 mg Capsules is used for the treatment of non-small cell lung cancer that is caused by a defect in a gene called ALK (anaplastic lymphoma kinase). The cancer must be (ALK)-positive as indicated by an FDA-approved test. This medicine blocks an enzyme called anaplastic lymphoma kinase (ALK). Some lung cancer cells have an overactive version of ALK. Blocking ALK with crizotinib can stop the cells growing but it only works in cancers with the overactive enzyme. About 1 in 20 people (5%) with non small cell lung cancer (NSCLC) have the overactive ALK enzyme.


Crizotinib 250 Mg Crizalk capsule works:

Crizotinib is a sort of pharmaceutical known as a protein kinase inhibitor. A kinase is a chemical that advances cell development. There are numerous sorts of kinases, which control distinctive periods of cell development. By obstructing a specific chemical from working, this prescription can moderate the development of disease cells.

Crizotinib works by focusing on and blocking receptors found on the disease cells called an anaplastic lymphoma kinase (ALK). This kinase is overactive in specific sorts of lung disease cells and it animates the development and spread of the growth cells. By restraining the activity of ALK, Generic Xalkori can moderate or stop cell development of disease cells and May likewise contract the tumor


Crizotinib 250 Mg Crizalk capsule works:

Crizotinib is a sort of pharmaceutical known as a protein kinase inhibitor. A kinase is a chemical that advances cell development. There are numerous sorts of kinases, which control distinctive periods of cell development. By obstructing a specific chemical from working, this prescription can moderate the development of disease cells.

Crizotinib works by focusing on and blocking receptors found on the disease cells called an anaplastic lymphoma kinase (ALK). This kinase is overactive in specific sorts of lung disease cells and it animates the development and spread of the growth cells. By restraining the activity of ALK, Pfizer Crizotinib can moderate or stop cell development of disease cells and May likewise contract the tumor.


CRIZOTINIB COMMON SIDE EFFECTS:

nausea, vomiting; diarrhea, constipation; swelling in your hands or feet; tired feeling; or vision problems such as blurred vision, increased sensitivity of your eyes to light, or seeing flashes of light or "floaters."

Call your doctor at once if you have:

    severe vision problems, including loss of vision;
    a headache with chest pain and severe dizziness, fainting, fast or pounding heartbeats;
    very slow heart rate; a light-headed feeling, like you might pass out; sudden chest pain or discomfort, wheezing, dry cough or a cough with mucus, feeling short of breath;
    fever, swollen gums, painful mouth sores, pain when swallowing, cold or flu symptoms; easy bruising or bleeding (nosebleeds, bleeding gums); or
    liver problems--nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.


Indian CRIZALK CRIZOTINIB Precautions & Warnings:


     ·       Pfizer crizotinib Capsules may cause dizziness, tiredness, or vision changes. These effects may be worse if you take it with alcohol or certain medicines. Use Pfizer Crizotinib with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

·         Crizotinib may cause vision changes such as blurred vision, flashes of light, floaters in your vision, or sensitivity to light. If this occurs, it usually begins within 1 week after starting crizotinib. Tell your doctor right away if you develop any of these symptoms.

·         Serious and sometimes fatal liver problems have occurred in patients taking crizotinib. Contact your doctor right away if you develop dark urine; persistent loss of appetite; right-sided stomach pain; severe or persistent tiredness, nausea, or vomiting; or yellowing of the skin or eyes.

·          Generic Xalkori Capsule may influence you to feel mixed up, languid or influence your vision. Try not to drive until the point that your vision is clear.

·      Crizalk Capsule ought to be utilized with alert in patients with serious kidney illness. Dosage alteration of Crizotinib Capsule might be required. It would be ideal if you counsel your specialist.This Capsule ought to be utilized with alert in patients with liver ailment. Measurements change of Crizalk 250mg Capsule might be required. If you don't mind counsel your specialist

·         Lab tests, including liver and heart function, blood pressure, blood electrolytes, eye exams, and complete blood cell counts, may be performed while you use crizotinib. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

·         PREGNANCY and BREAST-FEEDING: Crizotinib may cause harm to the fetus. Avoid becoming pregnant while you are taking it and for 90 days after you stop taking it. If you think you may be pregnant, contact your doctor right away. It is not known if this medicine is found in breast milk. Do not breast-feed while taking crizotinib.

This is not a complete list. Ask your health care provider for more information.

MEDICATION STORAGE REQUIREMENTS:

Store between 20°C and 25°C (68°F and 77°F); excursions are permitted between 15°C and 30°C (59°F and 86°F)

DRUG INTERACTIONS:


Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some medications can affect the removal of crizotinib from your body, which may affect how it works. Examples include azole antifungals (such as itraconazole), macrolide antibiotics (such as erythromycin), rifamycins (such as rifabutin), drugs for seizures (such as carbamazepine, phenytoin), St. John's wort, among others.


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