Gemcitabine Gemoxen Injection
Brand Name: Gemoxen
International Brand Name: Gemzar
Active Ingredient: Gemcitabine Injection
Manufacturer: Beacon Pharmaceutical Co. Ltd.
Packing: Pack of 1 Vial
Country of Origin: Bangladesh
Ovarian Cancer: Gemcitabine in combination with carboplatin is indicated for the treatment of patients with advanced ovarian cancer that has relapsed at least 6 months after completion of platinum-based therapy.
Breast Cancer: Gemcitabine in combination with paclitaxel is indicated for the first-line treatment of patients with metastatic breast cancer after failure of prior anthracycline-containing adjuvant chemotherapy unless anthracyclines were clinically contraindicated.
Non-Small Cell Lung Cancer: Gemcitabine is indicated in combination with cisplatin for the first-line treatment of patients with inoperable, locally advanced (Stage IIIA or IIIB), or metastatic (Stage IV) non-small cell lung cancer.
Pancreatic Cancer: Gemcitabine is indicated as first-line treatment for patients with locally advanced (nonresectable Stage II or Stage III) or metastatic (Stage IV) adenocarcinoma of the pancreas. Gemcitabine is indicated for patients previously treated with 5-FU.
Bone marrow suppression is manifested by leukopenia, thrombocytopenia, anaemia and myelosuppression. Mild GI effects; rashes; renal impairment, pulmonary toxicity, influenza-like symptoms; interstitial pneumonia, pulmonary oedema. Proteinuria, haematuria and haemolytic uraemic syndrome. Elevation of serum transaminase.
Precautions & Warnings:
Children, hepatic and renal impairment. May impair the ability to drive or operate machinery. Discontinue on 1st sign of microangiopathic haemolytic anaemia. Prolonged infusion time (>60 minutes) and more frequent than weekly dosing may increase toxicity. Monitor CBC before every dose. Increased risk of the haemolytic uraemic syndrome and/or thrombocytopenic purpura which may lead to irreversible renal failure.
Store at 25° C.
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