Adriamycin - Doxorubicin Injection
Brand Name: Adriamycin
Strength: 10mg / 50mg
Manufacturer: Pfizer, Inc.
Adriamycin is a cancer medication that interferes with the growth and spread of cancer cells in the body. It is classified as an antitumor antibiotic. Antitumor antibiotics are made from natural products produced by species of the soil fungus Streptomyces. These drugs act during multiple phases of the cell cycle and are considered cell-cycle specific.
MEDICINE USES :
Doxorubicin is used for the various treatments like Acute lymphoblastic leukemia (ALL), Acute myeloblastic leukemia (AML), Bone sarcoma, Breast cancer, Endometrial cancer, Gastric cancer, Head and neck cancer, Hodgkin lymphoma, Non-Hodgkin lymphoma, Liver cancer, Kidney cancer, Multiple myeloma, Neuroblastoma, Ovarian cancer, Small Cell Lung cancer, Soft tissue sarcoma, Thyomas, Thyroid cancer, Transitional cell bladder cancer, Uterine sarcoma, Wilms’ tumor and Waldenström macroglobulinemia
DOXORUBICIN COMMON SIDE EFFECTS:
Missed menstrual periods; darkening of your skin or nails; temporary hair loss; feeling weak or tired; mild nausea, diarrhea; or eye redness, puffy eyelids.
Call your doctor at once if you have:
feeling short of breath (even with mild exertion), swelling, rapid weight gain; fever, chills, body aches, flu symptoms, sores in your mouth and throat; pale skin, easy bruising, unusual bleeding, feeling like you might pass out;
chest pain, sudden cough, cough with foamy mucus, rapid breathing, coughing up blood; lower back pain, blood in your urine, little or no urinating;
Doxorubicin may cause your urine to turn a reddish-orange color. This side effect by itself is usually not harmful. However, call your doctor if you also have upper stomach pain, clay-colored stools, or jaundice (yellowing of your skin or the whites of your eyes).
Call your doctor for medical advice about side effects.
ADRIAMYCIN DOXORUBICIN INJECTION PRECAUTIONS :
· Before using Adriamycin, tell your doctor or pharmacist if you are allergic to it; or to lincomycin; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
· Before using this medication, tell your doctor or pharmacist your medical history, especially of: a current infection, low blood cell counts (e.g., anemia, neutropenia, thrombocytopenia), gout, heart problems (e.g., recent heart attack, heart failure, irregular heartbeat), a history of receiving any anthracycline-type drug (e.g., Adriamycin, idarubicin, daunorubicin, mitoxantrone), kidney problems, liver disease, severe mouth sores (stomatitis), radiation treatment (especially to the chest area).
· This medication may lower sperm count or may cause abnormal sperm to form, possibly causing infertility or birth defects. Consult your doctor for more details.
· This medication can affect menstruation in females and cause premature menopause. Consult your doctor or pharmacist for details.
· This medication is not recommended for use during pregnancy. It may harm an unborn baby. It is recommended that men and women use effective forms of birth control (e.g., condoms and birth control pills) while being treated with this medication and for 6 months after stopping the medication. Consult your doctor for more details and to discuss reliable forms of birth control.
Refrigerate unopened vials of Doxil at 2°– 8°C (36°– 46°F). Do not freeze.
Medicines that may harm the liver (eg, acetaminophen, mercaptopurine, methotrexate, ketoconazole, isoniazid, certain medicines for HIV infection) because the risk of Doxorubicin's side effects may be increased. Ask your doctor if you are unsure if any of your medicines might harm the liver
This document does not contain all possible interactions. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.