Spegra 400 mg

Medicine Detail

Brand: Spegra 400 mg

Content: Sofosbuvir 400 mg

Strength: 400 mg

From: Tablets

Manufacturer: Emcure Pharmaceuticals Ltd


Sofosbuvir is a nucleotide analog inhibitor of hepatitis C virus NS5B polymerase—the key enzyme mediating HCV RNA replication. The triphosphate form of sofosbuvir (GS-461203) mimics the natural cellular uridine nucleotide and is incorporated by the HCV RNA polymerase into the elongating RNA primer strand, resulting in viral chain termination.


Sofosbuvir is indicated for use by adults with chronic hepatitis C, meaning infection lasting more than six months. It is approved for people with HCV genotype. Sofosbuvir can be used by people being treated for hepatitis C for the first time (known as 'treatment-naive'). Sofosbuvir can be used by people with all stages of liver disease including compensated and decompensated cirrhosis. However, it works better for people with less advanced liver damage. People with chronic hepatitis C who are awaiting or have received a liver transplant tolerate sofosbuvir better than older medications.


During treatment with sofosbuvir in combination with ribavirin or with peginterferon Alfa and ribavirin, the most frequently reported adverse drug reactions were consistent with the expected safety profile of ribavirin and peginterferon Alfa treatment, without increasing the frequency or severity of the expected adverse drug reactions.

Sovaldi has moderate influence on the ability to drive and use machines. Patients should be informed that fatigue and disturbance in attention, dizziness and blurred vision have been reported during treatment with sofosbuvir in combination with peginterferon Alfa and ribavirin.


Spegra 400 Mg is known as Indian Sovaldi. We have all Indian Sovaldi 400 Mg medicines such as Hepcinat, Myhep, Sovihep, Hepcvir, Resof & spegra. We are Capable to Export all kinds of Anti Cancer Medicine to the world.

Sovaldi in combination with ribavirin for 24 weeks can be considered as a therapeutic option for CHC patients with genotype 1 infection who are ineligible to receive an interferon-based regimen. Treatment decision should be guided by an assessment of the potential benefits and risks for the individual patient.


Tell your doctor right away if you have any serious side effects, including signs of low red blood cell count (such as unusual tiredness, rapid breathing, pale skin, shortness of breath, fast heartbeat).

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

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