Tenvir Tenofovir fumarate Tablets

Medicine Detail

Brand name: Tenvir
Active ingredient:  Tenofovir Disoproxil Fumarate IP
Manufacturer:  Cipla Limited
Form: Tablets
Strength: 300 mg
Packing: Pack of 30 tablets


Tenvir 300mg is an antiviral drug belonging to class nucleoside reverse transcriptase inhibitors (NRTIs). Its structure closely resembles the natural structure of viral DNA, that helps it to incorporate itself into the viral DNA. By doing so, it blocks the activity of an important viral enzyme reverse transcriptase which is involved in the replication of viral DNA, a process essential for survival of the virus.


Cipla Tenofovir is used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). It is not a cure for HIV or AIDS. It is also used to treat chronic hepatitis B.


Call your doctor at once if you have:

    sore throat, flu symptoms, easy bruising or unusual bleeding;
    kidney problems--little or no urination, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath; or
    liver problems--nausea, upper stomach pain, itching, tiredness, loss of appetite, dark urine, clay-colored stools, jaundice.

Tenofovir may increase your risk of certain infections or autoimmune disorders by changing the way your immune system works. Symptoms may occur weeks or months after you start treatment with Tenofovir. Tell your doctor if you have:

    signs of a new infection--fever, night sweats, swollen glands, mouth sores, diarrhea, stomach pain, weight loss;
    chest pain (especially when you breathe), dry cough, wheezing, feeling short of breath;
    rapid heart rate, feeling anxious or irritable, weakness or prickly feeling, problems with balance or eye movement;

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.


    If you have HIV infection, you should be tested for HBV infection before you start to take Tenvir. If you have HBV infection, you should be tested for HIV infection before you start to take Tenvir.
    Keep a list of all the medicines that you take. Make a new list each time medicines are added or stopped. Find out about medicines that should not be taken while you are using Tenvir. Be sure that each of your health care providers knows all the medicines that you are taking.
    Tenvir does not stop the spread of HIV or HBV to others through blood or sexual contact.
    Tell your doctor or dentist that you take Tenofovir before you receive any medical or dental care, emergency care, or surgery.
    Lab tests, including liver and kidney function and bone mineral density, may be performed while you use Tenofovir. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
    PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Tenofovir while you are pregnant. It is not known if this medicine is found in breast milk. Mothers infected with HIV should not breast-feed. There is a risk of passing the HIV infection or Tenofovir to the baby. Do not breast-feed while taking this medicine.

This is not a complete list. Ask your health care provider for more information.


Store at 25°C (77°F)


Some MEDICINES MAY INTERACT with Tenvir. Tell your health care provider if you are taking any other medicines, especially any of the following:

Acyclovir, cidofovir, ganciclovir, valacyclovir, valganciclovir, or other medicines that may harm the kidneys (eg, aminoglycoside antibiotics [eg, gentamicin], amphotericin B, cyclosporine, NSAIDs [eg, ibuprofen], tacrolimus, vancomycin) because they may increase the risk of Tenvir's side effects.
Adefovir, lopinavir/ritonavir or other HIV protease inhibitors (eg, atazanavir), or medicines that contain Tenofovir because they may increase the risk of its side effects
Didanosine because the risk of its side effects may be increased by Tenofovir

This document does not contain all possible interactions. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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